Abrasive Silica -Silica Dioxide (MIA type)
Silica Dioxide (MIA type) is a synthetic, amorphous silica appearing as a white, free-flowing powder. It meets the test requirements for silicon dioxide as described in the latest edition of United States Pharmacopoeia/National Formulary (USP/NF) and for hydrated silicon dioxide. Silica Dioxide (MIA type) is a low pore volume gel with a very large internal surface area. It has a strong affinity for moisture even at very low humidity levels. Silica Dioxide (MIA type) is particularly recommended as a free flow and tabletting additive for pharmaceutical products where humidity must be kept to a minimum. It has excellent compatibility with active ingredients.
* Increased Physical Stability of hygroscopic systems (API, Polymer, Natural Extract
* Intragranular Desiccant / Moisture control up to 80% RH
* Stabilise the water in your formulation to protect API
* High surface area 700m2/g provides monolayered water under all RH%.
Properties
* Low dust
* Easy to disperse/handle
* Porosity is developed intra-particle
* Porosity available after compression
* Higher available surface area
Applications
Glidant
* Anti-caking agent* Improves flow properties and homogeneity
Coating
* Matting agent* Wetting agent: capillary wetting, aqueous and gastric wetting
Tabletting Aid
* Improves tablet hardness, tensile strength, structural stability and reduces friability* Ensures uniform tablet weight
Wetting Agent/Disintegrant Aid
* Helps tablet break up faster by adsorbing moisture* Wetting agent: aqeuous and gastric wetting, ODT’s
* Permeabilising agent
Desiccant/Moisture control
* Insures long term product storage stability* Adsorbs moisture and oils keeping powders dry to prevent degradation